Resveratrol
What is Resveratrol?
Resveratrol is a natural phenol and a type of stilbenoid, which is a phytoalexin produced by several plants in response to injury or when the plant is under attack by pathogens, such as bacteria or fungi. It is found in various foods, including grapes, red wine, peanuts, pistachios, blueberries, and cranberries. Resveratrol has been studied for its potential therapeutic use, with little evidence of anti-disease effects or health benefits in humans. It has been identified as a pan-assay interference compound, which produces positive results in many different laboratory assays. Its ability for varied interactions may be due to direct effects on cell membranes (1) (2) (4) (5) (6).
Health Benefits
Resveratrol has been studied for its potential health benefits, including:
- Anti-inflammatory and antioxidant properties
- Cardiovascular disease prevention
- Anti-aging effects
- Memory improvement
- Joint pain relief due to osteoarthritis
However, there is little evidence to support these uses in humans (1) (2) (4) (5).
Standard Dose and Maximum Dose per Day
The standard dose of resveratrol varies depending on the individual's needs and response to the medication. The dosage may range from 250 mg to 1500 mg per day. It is important to follow the instructions provided by the healthcare professional or the supplement manufacturer. The maximum recommended dose is 2000 mg per day (1) (2) (4) (5).
Time of Day and With or Without Food
There is no specific information available about the best time of day to take resveratrol or whether it should be taken with or without food. It is recommended to follow the instructions provided by the healthcare professional or the supplement manufacturer (3).
Side Effects
Resveratrol is generally considered safe when taken in recommended doses. However, high doses may cause gastrointestinal side effects, such as diarrhea, nausea, and abdominal pain. Resveratrol may also interact with blood thinners, such as warfarin, and increase the risk of bleeding. It may also interact with other medications, such as aspirin, and supplements, such as garlic and ginkgo biloba. It is important to inform the healthcare professional about all the medications and supplements being taken (1) (2) (4) (5).
Human Studies
Resveratrol has been studied in humans for its potential health benefits, but there is little evidence to support its use in disease prevention or treatment. More research is needed to fully understand the benefits and safety profile of resveratrol in humans (1) (2) (4) (5) (6).
Summary
To summarize, resveratrol is a natural phenol and a type of stilbenoid found in various foods, including grapes, red wine, peanuts, pistachios, blueberries, and cranberries. It is available as a dietary supplement in powder, capsule, tablet, or softgel form. Resveratrol has been studied for its potential health benefits, including anti-inflammatory and antioxidant properties, cardiovascular disease prevention, anti-aging effects, memory improvement, and joint pain relief due to osteoarthritis. However, there is little evidence to support these uses in humans. Resveratrol is generally considered safe when taken in recommended doses, but high doses may cause gastrointestinal side effects and may interact with blood thinners and other medications and supplements. More research is needed to fully understand the benefits and safety profile of resveratrol in humans.
Citations:
(1) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164842/
(2) https://en.wikipedia.org/wiki/Resveratrol
(3) https://www.amazon.com/Resveratrol-Supplement-Formula-Quercetin-Capsules/dp/B01N3LZY3O
(4) https://www.webmd.com/vitamins/ai/ingredientmono-307/resveratrol
(5) https://www.mskcc.org/cancer-care/integrative-medicine/herbs/resveratrol
(6) https://lpi.oregonstate.edu/mic/dietary-factors/phytochemicals/resveratrol