Phosphatidylserine
What is Phosphatidylserine?
Phosphatidylserine (PS) is a type of phospholipid that is found in high amounts in the brain, where it contributes to cognitive functioning (3)(4). It is part of the cell structure in the body and can be synthesized as well as consumed through the diet (5). PS is a fatty substance that protects nerve cells in the brain and enables them to communicate with each other (6). The amount of natural PS in the body decreases as you get older, and some people choose to take this supplement to increase the amount of PS in their brain (6).
Dosage
The dosage of phosphatidylserine depends on the specific medication it is being used in and the patient's medical condition (2)(3). It is available in various forms, including capsules, tablets, and injections (2). The recommended dosage for each form may vary, and it is important to follow the instructions provided by the healthcare provider or the manufacturer (2).
Side Effects
Phosphatidylserine is generally considered safe when taken orally or applied topically (2)(3). However, it may cause side effects, including stomach upset, diarrhea, nausea, and sweating (2)(4). If you experience any serious side effects, such as an allergic reaction, seek medical attention immediately (2).
Interactions
There are no known drug interactions with phosphatidylserine (2). However, it is important to inform your healthcare provider of all medications you are taking, including prescription, over-the-counter, and herbal products, before starting phosphatidylserine treatment (2).
Time of Day and With or Without Food
Phosphatidylserine can be taken with or without food (2). The tablets or capsules should be swallowed whole and not chewed, broken, or crushed (2).
Human Studies
Phosphatidylserine is a fatty substance that protects nerve cells in the brain and enables them to communicate with each other (3)(4). The safety and efficacy of phosphatidylserine have been evaluated in clinical trials, and the results have shown that it can improve memory, cognitive function, attention, and ability to focus in aging people with declining thinking skills (4)(5). PS has also been studied for its potential benefits in treating Alzheimer's disease, depression, anxiety, ADHD, and other conditions, but more research is needed to confirm these effects (4)(5).
To summarize, Phosphatidylserine is a type of phospholipid that is found in high amounts in the brain, where it contributes to cognitive functioning. The dosage of phosphatidylserine depends on the specific medication it is being used in and the patient's medical condition. Phosphatidylserine can be taken with or without food. Phosphatidylserine is generally considered safe when taken orally or applied topically, but it may cause side effects such as stomach upset, diarrhea, nausea, and sweating. There are no known drug interactions with phosphatidylserine. The safety and efficacy of phosphatidylserine have been evaluated in clinical trials, and the results have shown that it can improve memory, cognitive function, attention, and ability to focus in aging people with declining thinking skills. PS has also been studied for its potential benefits in treating Alzheimer's disease, depression, anxiety, ADHD, and other conditions, but more research is needed to confirm these effects.
Citations:
(1) [https://pubmed.ncbi.nlm.nih.gov/25933483/]
(2) [https://www.verywellmind.com/the-benefits-of-phosphatidylserine-89496]
(3) [https://examine.com/supplements/phosphatidylserine/]
(4) [https://www.webmd.com/vitamins-and-supplements/phosphatidylserine-uses-and-risks]
(5) [https://www.webmd.com/vitamins/ai/ingredientmono-992/phosphatidylserine]
(6) [https://my.clevelandclinic.org/health/drugs/25129-phosphatidylserine]