Pemirolast
What is Pemirolast?
Pemirolast is a medication used to treat allergies such as hay fever and allergic conjunctivitis (5). It is a mast cell stabilizer that works by preventing certain types of inflammatory cells from releasing irritating substances that cause allergic symptoms (4). Pemirolast is marketed under the trade names Alegysal and Alamast (3).
Dosage
The dosage of pemirolast depends on the specific medication it is being used in and the patient's medical condition (2)(6). Pemirolast is usually administered as an ophthalmic solution, with one or two drops in each affected eye, four times a day (6). The duration of treatment depends on the severity of the condition and the response to treatment (6).
Side Effects
Pemirolast may cause side effects, including eye irritation, burning, stinging, itching, redness, dryness, and tearing (2)(4)(6). Other potential side effects might include headache, nausea, and bad taste in the mouth (2). If you experience any serious side effects, such as an allergic reaction, seek medical attention immediately (2).
Interactions
There are no known drug interactions with pemirolast (2). However, it is important to inform your healthcare provider of all medications you are taking, including prescription, over-the-counter, and herbal products, before starting pemirolast treatment (2).
Time of Day and With or Without Food
Pemirolast is usually administered as an ophthalmic solution, with one or two drops in each affected eye, four times a day (6). It can be taken with or without food (6).
Human Studies
Pemirolast is a mast cell stabilizer used to treat allergies such as hay fever and allergic conjunctivitis (1)(3)(4)(5). It works by preventing certain types of inflammatory cells from releasing irritating substances that cause allergic symptoms (4). The safety and efficacy of pemirolast have been evaluated in clinical trials, and the results have shown that it can effectively prevent and relieve ocular manifestations of allergic conjunctivitis (1)(4)(6).
To summarize, Pemirolast is a medication used to treat allergies such as hay fever and allergic conjunctivitis. The dosage of pemirolast depends on the specific medication it is being used in and the patient's medical condition. Pemirolast can be taken with or without food. Pemirolast may cause side effects, including eye irritation, burning, stinging, itching, redness, dryness, and tearing. There are no known drug interactions with pemirolast. The safety and efficacy of pemirolast have been evaluated in clinical trials, and the results have shown that it can effectively prevent and relieve ocular manifestations of allergic conjunctivitis.
Citations:
(1) [https://www.sciencedirect.com/topics/medicine-and-dentistry/pemirolast]
(2) [https://www.drugs.com/mtm/pemirolast-ophthalmic.html]
(3) [https://en.wikipedia.org/wiki/Pemirolast]
(4) [https://www.mayoclinic.org/drugs-supplements/pemirolast-ophthalmic-route/description/drg-20065356]
(5) [https://go.drugbank.com/drugs/DB00885]
(6) [https://www.rxlist.com/alamast-drug.htm]