NMN
What is NMN?
Nicotinamide mononucleotide (NMN) is a molecule that is naturally produced in the body and is involved in the production of nicotinamide adenine dinucleotide (NAD+), a coenzyme that plays a crucial role in cellular metabolism and energy production (1). NMN is also found in various animal and plant food sources, including broccoli, avocados, tomatoes, edamame, and mushrooms (1) (3) (4) (6). NMN is available as a dietary supplement and is marketed as an anti-aging supplement, claiming to improve cellular health and function (2).
Dosage
The optimal dosage of NMN is not yet established, and research is ongoing to determine the appropriate dosage for humans. However, some studies have used doses ranging from 100 to 500 mg per day (3). It is important to follow the instructions on the product label and consult a doctor or pharmacist for any clarification.
Side Effects
NMN is generally considered safe when taken in recommended doses. However, potential side effects might include gastrointestinal issues, such as nausea, diarrhea, and abdominal pain (4). More research is needed to determine the long-term safety of NMN supplementation.
Interactions
There is limited information available on the potential interactions of NMN with other medications or supplements. It is recommended to consult a doctor or pharmacist before combining NMN with other drugs or supplements.
Time of Day and With or Without Food
The specific time of day to take NMN may vary depending on the individual and the product. It is best to follow the instructions provided by the manufacturer.
Human Studies
Research on the effects of NMN on humans is still in its early stages, and more studies are needed to determine its efficacy and safety. Some animal studies have shown promising results, suggesting that NMN supplementation may improve metabolic function, increase energy expenditure, and improve insulin sensitivity (5). However, more research is needed to determine whether these effects translate to humans.
To summarize, NMN is a molecule that is naturally produced in the body and is involved in cellular metabolism and energy production. It is also found in various animal and plant food sources. The optimal dosage and long-term safety of NMN supplementation are not yet established, and more research is needed to determine its efficacy and safety in humans.
Citations:
(1) https://hello100.com/nmn-foods/
(2) https://www.sciencedirect.com/science/article/pii/S1550413116304958
(3) https://pubmed.ncbi.nlm.nih.gov/37273100/
(4) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238909/
(5) https://www.forbes.com/health/healthy-aging/nicotinamide-mononucleotide/
(6) https://partiqlar.com/what-foods-contain-nmn-naturally/