Luteolin
What is Luteolin?
Luteolin is a flavonoid, a type of plant pigment that belongs to a group of naturally occurring compounds called flavonoids that are found widely in the plant kingdom (1) (3). It is present in various fruits and vegetables, such as parsley, thyme, celery, and broccoli (2). Luteolin has been attributed with numerous health-promoting properties including anti-cancer, antioxidant, anti-inflammatory, and neuroprotective action (4) (5) (6). It has been studied for its potential in the prevention and treatment of diverse ailments, such as cancer, chronic pain, and cardiovascular disease (1) (4) (6).
Dosage and Timing
While there is no standardized dosage for luteolin, the ideal dose can vary based on the individual and the purpose for which the supplement is being used (1). Luteolin supplements can be found in various forms, including capsules, tablets, and powders (2). The timing for consuming luteolin may be contingent on the supplement's intended purpose. It's recommended to follow the instructions provided by the manufacturer or seek advice from a healthcare professional for optimal usage.
Side Effects and Interactions
In typical doses, luteolin is considered to be safe (1). However, excessive intake can lead to side effects such as diarrhea, nausea, stomach pain, mood alterations, headache, and joint pain (5). Luteolin might have interactions with specific medications, especially blood thinners, enhancing the risk of bleeding (1). Hence, before incorporating luteolin supplements into one's regimen, it's crucial to notify the doctor about any other medications being taken.
Human Studies
Luteolin has been researched in human subjects for an array of conditions including, but not limited to, chronic pain, cancer, and cardiovascular diseases (1) (4) (6). Nevertheless, to comprehensively understand its advantages and potential hazards, further research is warranted (1).
In summary, Luteolin is a flavonoid found in several fruits and vegetables, accredited with multiple health benefits such as anti-cancer, antioxidant, anti-inflammatory, and neuroprotective properties. It is being examined for its potential to ward off and cure various diseases including cancer, chronic pain, and cardiovascular issues. The dosage of luteolin isn't standardized and can vary based on individual needs and the specific purpose for use. Generally deemed safe in moderate doses, high intake can lead to side effects. Luteolin may interact with specific medications, so it's crucial to keep medical professionals informed if one decides to take this supplement. While luteolin has been studied in human subjects for numerous conditions, more extensive research is required to elucidate its benefits and risks comprehensively.
Citations:
(1) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615542/
(2) https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/luteolin
(3) https://en.wikipedia.org/wiki/Luteolin
(4) https://www.frontiersin.org/articles/10.3389/fpain.2023.1114428
(5) https://www.frontiersin.org/articles/10.3389/fnmol.2019.00041
(6) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635727/