Lumbrokinase
What is Lumbrokinase?
Lumbrokinase consists of fibrinolytic enzymes identified in earthworm varieties such as Lumbricus bimastus and Lumbricus rubellus (1). Its discovery traces back to 1991 in earthworm saliva. Recognized and approved as an antithrombotic agent in Asia, lumbrokinase contributes to reduced intra-abdominal adhesion and minimized peritoneal thickening, owing to its enhanced fibrinolytic activity and reduced fibroblast impact (2). Its potential to dissolve fibrinogen and fibrin directly positions it as an agent promoting circulation and holistic well-being (4) (5).
Uses and Benefits
- Cardiovascular health: Lumbrokinase exhibits the potential to enhance circulation and fortify cardiovascular health (4) (5).
- Fibrinolytic: Its fibrinolytic properties enable lumbrokinase to dissolve fibrinogen and fibrin directly (4) (5).
- Anti-thrombotic: In Asia, lumbrokinase has gained recognition as an antithrombotic agent (1).
Dosage
Lumbrokinase's recommended intake is one capsule 1-3 times daily on an empty stomach (3). In cases of pronounced hypoperfusion, 2 capsules, taken thrice daily for 3-6 weeks, might be suggested (3). For children, the stipulated dose is 1 capsule per 8Kg (approximately 17 pounds) daily (3). Prior consultation with a healthcare expert is recommended before starting lumbrokinase.
A dose of 40 mg of lumbrokinase per day is equivalent to 800,000 LK units per day.
Side Effects
Usually, lumbrokinase is well-tolerated as a dietary supplement (3) (6). However, individuals allergic to it should refrain from its consumption (3). It's essential to liaise with a medical professional before its intake, especially if on medication, pregnant, or facing surgery or bleeding risks (3).
Interactions
Information on lumbrokinase's interaction with other drugs or supplements is scant. Engaging with a healthcare specialist is advised before pairing lumbrokinase with other medications or supplements.
Time of Day and With or Without Food
It's ideal to consume lumbrokinase on an empty stomach (3).
Human Studies
While lumbrokinase has undergone research in Asia, confirming its antithrombotic properties, a broader spectrum of research is required to validate its safety and efficacy in human applications (1).
To conclude, lumbrokinase, derived from earthworm species, demonstrates attributes beneficial for cardiovascular health and circulation. Generally perceived as safe for dietary supplementation, it's imperative to seek medical counsel prior to its consumption, especially if other medications are involved, or if one is pregnant, prone to bleeding, or is undergoing surgery. The recommended intake is on an empty stomach. Further studies are crucial to understand lumbrokinase's interactions with other drugs and its comprehensive efficacy and safety in humans.
Citations:
(1) https://en.wikipedia.org/wiki/Lumbrokinase
(2) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851794/
(3) https://www.researchednutritionals.com/product/boluoke-lumbrokinase-120-caps/
(4) https://www.amazon.com/Double-Wood-Supplements-Lumbrokinase-Supplement/dp/B0B7KHRMR3
(5) https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-022-06200-4
(6) https://www.amazon.com/Dr-Mercola-Lumbrokinase-Supplement-Servings/dp/B07QB71RZ6