Glycine

What is Glycine?

Glycine, a notable amino acid, possesses a solitary hydrogen atom as its side chain (1)(3)(5). Its reputation as the most rudimentary stable amino acid is underscored by its chemical composition, NH2‐CH2‐COOH (1). As one of the proteinogenic amino acids, glycine is instrumental in protein synthesis within the body (1)(3)(5). Remarkably, all codons initiating with GG (GGU, GGC, GGA, GGG) encode for it (1). Natural sources abundant in glycine encompass meat, fish, dairy, legumes, fruits, and vegetables (3)(5).

Uses of Glycine

Studies have unveiled a plethora of potential health advantages attributed to glycine:

• It plays a pivotal role in synthesizing proteins vital for tissue and hormone upkeep (5).
• Owing to its role in the transmission of chemical signals in the brain, it’s eyed for conditions such as schizophrenia and enhancing memory (3).
• It’s recognized for its capability to curtail lung inflammation and augment survival rates (2).
• Glycine’s benefits extend to ameliorating liver function, mending liver injuries, and warding off potential liver damages (2).
• It participates in neutralizing specific free radicals (5).
• It’s essential for the optimal function of certain enzymes (5).
• Glycine aids in reactivating vitamins C and E (5).
• It plays a part in mercury expulsion from the brain (5).
• It’s vital for the liver and gallbladder in managing fats (5).

Dosage

The prescribed glycine dosage hinges on the specific condition under treatment and the individual's physique (2)(3)(5). Glycine is procurable in diverse forms, including oral supplements, injections, and inhalation (2)(3). Ordinarily, the oral dose ranges between 2 grams and 60 grams daily (3). Treatment duration is typically extended, contingent on the ailment (2).

Side Effects

Glycine is predominantly well-tolerated, with infrequent side effects (2)(3). Potential side effects stemming from oral intake might encompass gastrointestinal issues, nausea, and diarrhea (2)(3).

Interactions

There's potential for glycine to interact with specific medications. Hence, prior medical consultation is imperative before amalgamating glycine with other drugs or supplements (3).

Summary:
Glycine is distinguished by its single hydrogen atom side chain, making it the simplest stable amino acid with the formula NH2‐CH2‐COOH. Being proteinogenic, it is indispensable for the body's protein production. Its wide range of potential health benefits spans from tissue repair and hormone maintenance to brain signaling and liver function enhancement. While side effects are rare, it's prudent to consult with medical professionals before combining it with other medications. Natural food sources rich in glycine encompass various meats, fish, dairy products, legumes, fruits, and vegetables.

Citations:
(1) https://en.wikipedia.org/wiki/Glycine
(2) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350494/
(3) https://www.webmd.com/vitamins/ai/ingredientmono-1072/glycine
(4) https://glycine-watch.ch
(5) https://www.healthline.com/nutrition/glycine
(6) https://www.webmd.com/diet/health-benefits-glycine

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