Cromolyn Sodium (Cromoglicate)
What is Cromolyn Sodium (Cromoglicate)?
Cromolyn Sodium, also known as Cromoglicate, is a medication used to manage bronchial asthma, allergic rhinitis, and certain allergic eye conditions such as vernal conjunctivitis, keratitis, and keratoconjunctivitis (1)(4)(5). It is a mast cell stabilizer that prevents the subsequent release of inflammatory mediators, including histamine and leukotrienes, which cause allergic symptoms and bronchoconstriction (1)(4)(5). Cromolyn Sodium was derived from furanochromone, khellin, a natural drug product extracted from an eastern Mediterranean herb called Ammi visnaga (1).
Dosage
The dosage of Cromolyn Sodium varies depending on the condition being treated and the patient's weight (1). The standard dose of Cromolyn Sodium is 1-2 ampules (20-40 mg) four times daily, taken orally (1).
Side Effects
Cromolyn Sodium is generally well-tolerated, and side effects are uncommon (1)(3)(5). Some possible side effects with oral use include throat irritation, cough, and gastrointestinal upset (1)(5).
Interactions
Cromolyn Sodium may interact with certain medications, and it should be used with caution in individuals with certain medical conditions (1)(4). Prior consultation with a medical expert is recommended before combining Cromolyn Sodium with other drugs or supplements.
Human Studies
Cromolyn Sodium has been studied for its potential health benefits, including managing bronchial asthma, allergic rhinitis, and certain allergic eye conditions such as vernal conjunctivitis, keratitis, and keratoconjunctivitis (1)(4)(5). It is a mast cell stabilizer that prevents the subsequent release of inflammatory mediators, including histamine and leukotrienes, which cause allergic symptoms and bronchoconstriction. Cromolyn Sodium is generally well-tolerated, and side effects are uncommon. However, more research is needed to determine the full extent of its therapeutic potential.
To summarize, Cromolyn Sodium, also known as Cromoglicate, is a medication used to manage bronchial asthma, allergic rhinitis, and certain allergic eye conditions such as vernal conjunctivitis, keratitis, and keratoconjunctivitis. It is a mast cell stabilizer that prevents the subsequent release of inflammatory mediators, including histamine and leukotrienes, which cause allergic symptoms and bronchoconstriction. The standard dose of Cromolyn Sodium is 1-2 ampules (20-40 mg) four times daily, taken orally. Cromolyn Sodium is generally well-tolerated, and side effects are uncommon. Cromolyn Sodium may interact with certain medications, and it can be taken at any time of day, with or without food. Cromolyn Sodium has been studied for its potential health benefits, including managing bronchial asthma, allergic rhinitis, and certain allergic eye conditions such as vernal conjunctivitis, keratitis, and keratoconjunctivitis. However, more research is needed to determine the full extent of its therapeutic potential.
Citations:
(1) https://www.ncbi.nlm.nih.gov/books/NBK557473/
(2) https://go.drugbank.com/drugs/DB01003
(3) https://pubmed.ncbi.nlm.nih.gov/4212341/
(4) https://en.wikipedia.org/wiki/Cromoglicic_acid
(5) https://www.sciencedirect.com/topics/medicine-and-dentistry/cromoglycate-disodium
(6) https://www.sciencedirect.com/topics/immunology-and-microbiology/cromoglicic-acid
Cromolyn used for LC neuroinflammation
https://pharmd.substack.com/p/nasalcrom-for-neuroinflammation?utm_source=profile&utm_medium=reader2
