Astragalus
What is Astragalus?
Astragalus is a type of flowering plant that belongs to the legume family Fabaceae and is native to temperate regions of the Northern Hemisphere (1)(3). The root of Astragalus membranaceus has been used for centuries in traditional Chinese Medicine (TCM) (1)(2)(6). Astragalus is considered an adaptogen, which is a class of natural substances believed to stimulate the body's resistance to various stressors (1). The chemicals in astragalus appear to activate the immune system and reduce swelling (1). Astragalus is commonly used for various conditions, but scientific evidence to substantiate these uses is lacking (1). Various forms of astragalus supplements are available in the market (4).
Clinical Studies
Many clinical trials have investigated the use of astragalus for diverse health conditions (1). Some astragalus preparations might aid in managing insomnia and stress (1). However, its effects on anxiety are still under debate (1). Limited studies suggest astragalus might improve testosterone levels and sperm quality when consumed over 2 to 4 months (1). Yet, robust evidence to assert astragalus's efficacy in other health domains remains elusive (1).
Dosage
The dosage recommendations for astragalus depend on the condition in focus and individual factors like weight (1). Typically, an oral dose of up to 60 grams per day for a duration of up to 4 months is advised (6).
Side Effects
Astragalus is usually well-tolerated, with adverse reactions being rare (1)(6). Some individuals might experience symptoms like rashes, itching, nasal issues, or gastrointestinal discomfort (6).
Interactions
Astragalus could interfere with medications meant to suppress the immune system, such as tacrolimus and cyclosporine (4). It's imperative to consult a healthcare expert before co-administering astragalus with other treatments.
Time of Day and With or Without Food
No specific time has been recommended for astragalus consumption (1). It can be taken with or without food (1).
Human Studies
While astragalus has been the subject of many human studies, many are limited in their scope or employ various astragalus formulations (1). Some findings suggest its potential in treating insomnia and stress (1), but its impact on anxiety remains inconclusive (1). Limited studies indicate potential benefits in testosterone levels and sperm health after 2 to 4 months of intake (1). Still, conclusive evidence regarding its broad-scale benefits remains to be established (1).
In essence, Astragalus, native to the Northern Hemisphere, has deep roots in traditional Chinese Medicine. Classified as an adaptogen, it's believed to fortify the body against various stressors. The advised oral dose can go up to 60 grams daily for up to 4 months. Generally, astragalus is well-received, but some might experience minor side effects. Interactions with immune-suppressing drugs warrant caution. It can be consumed anytime and with or without meals. While it has been the focus of many human studies, definitive evidence regarding its array of benefits is still in the making.
Citations:
(1) https://www.webmd.com/vitamins/ai/ingredientmono-963/astragalus
(2) https://www.mountsinai.org/health-library/herb/astragalus
(3) https://en.wikipedia.org/wiki/Astragalus_(plant)
(4) https://www.merckmanuals.com/home/special-subjects/dietary-supplements-and-vitamins/astragalus
(5) https://www.mskcc.org/cancer-care/integrative-medicine/herbs/astragalus
(6) https://www.nccih.nih.gov/health/astragalus